Reduced genioglossus muscle activity caused by fluid overload in anesthetized rats
نویسندگان
چکیده
منابع مشابه
Control of genioglossus muscle inspiratory activity.
Tonic and phasic inspiratory genioglossus (GG) electromyographic activity (EMG) was recorded from 13 anesthetized rabbits during unstimulated breathing. Integrated GG EMG peaked earlier in inspiration and presented a more rounded contour than integrated diaphragmatic (DIA) EMG. Spontaneous augmented deep inspirations (sighs) showed a biphasic pattern in both GG and DIA EMGs. Hyperventilation ab...
متن کاملRole of endogenous serotonin in modulating genioglossus muscle activity in awake and sleeping rats.
RATIONALE Exogenous serotonin at the hypoglossal motor nucleus (HMN) stimulates genioglossus (GG) muscle activity. However, whether endogenous serotonin contributes to GG activation across natural sleep-wake states has not been determined, but is relevant given that serotonergic neurons have decreased activity in sleep and project to pharyngeal motoneurons. OBJECTIVES To determine the role of...
متن کاملGenioglossus muscle activity and serotonergic modulation of hypoglossal motor output in obese Zucker rats.
Obese Zucker rats have a narrower and more collapsible upper airway compared with lean controls, similar to obstructive sleep apnea (OSA) patients. Genioglossus (GG) muscle activity is augmented in awake OSA patients to compensate for airway narrowing, but the neural control of GG activity in obese Zucker rats has not been investigated to determine whether such neuromuscular compensation also o...
متن کاملSystemic vs. central administration of common hypnotics reveals opposing effects on genioglossus muscle activity in rats.
STUDY OBJECTIVES To determine if systemic administration of selected sedative-hypnotics that modulate the function of the y-amino-butyric acid-A (GABAA) receptor can: (i) delay arousal thereby allowing genioglossus (GG) activity to increase more in response to respiratory stimulation during sleep, (ii) also cause the robust increase in GG activity during undisturbed sleep recently observed with...
متن کاملGenioglossus muscle activity and inspiratory timing in obstructive sleep apnea.
Atypical tongue muscle activity during sleep may contribute to the development of obstructive sleep apnea (OSA). Inspiratory genioglossus (GG) muscle activity was investigated in 10 OSA adults and 4 symptom-free controls. On the basis of overnight monitoring during nonREM sleep, the duration of the inspiratory GG activity and the total GG activity cycle is shorter in patients with OSA. The dura...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2020
ISSN: 2051-817X,2051-817X
DOI: 10.14814/phy2.14445